Lei Jin

Epidemiology on reproductive and child health

Birth defect preventive study  

Environment and reproductive health

1. Prevention strategy of developmental disabilities under background of Population Aging. 2021–2024. Funding source: Major Project of the National Social Science Fund of China. Role: key investigator.

2. Effects and key mechanism of environment and epi-genetic factors on selected birth defects. 2021–2024，Funding source: Ministry of Science and Technology, the National Key Research and Development Program of China. Role: key investigator.

3. Impact and key mechanism of maternal endocrine metabolism on early health of offspring. 2021–2024. Funding source: Ministry of Science and Technology, the National Key Research and Development Program of China. Role: key investigator.

4. Cohort Study of The Effects of Environmental and Behavioral Factors on Embryonic Development and Maternal Health Based on External Exposure Surveillance, 2018–2021. Funding source: Ministry of Science and Technology, the National Key Research and Development Program of China. Role: key investigator.

5. Environmental Determinants and prevention strategy of Major Birth Defects. 2016–2021. Funding source: Ministry of Science and Technology, the National Key Research and Development Program of China. Role: Key Investigator.

（*:corresponding author）

1. Liu M, Yu J, Su Z, Sun Y, Liu Y, Xie Q, Li Z, Wang L, Zhang J, Jin L*, Ren A*. Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single‑nucleotide polymorphisms of fetal MTHFR and SOD2: a case–control study [J]. Environmental Health, 2021, 20(66): 1-10. Doi: https://doi.org/10.1186/s12940-021-00752-9.

2. Zhang J, Jin L, Wang D, Wang C, Tong M, Yu J, Meng W, Ren A, Jin L*. Maternal periconceptional folic acid supplements use and fetus risk for limb defects [J]. Paediatr Perinat Epidemiol. 2021;00:1–9. Doi：https://doi.org/10.1111/ppe.12775.

3. Yin S; Sun Y; Yu J; Su Z; Tong M; Zhang Y; Liu J; Wang L; Li Z; Ren A*; Jin L*; Prenatal exposure to organochlorine pesticides is associated with increased risk for neural tube defects [J]. The Science of the Total Environment, 2021,770:145284. Doi: 10.1016/j.scitotenv.2021.145284

4. Tong M; Yu J; Liu M; Li Z; Wang L; Yin C; Ren A; Chen L*; Jin L*; Total mercury concentration in placental tissue, a good biomarker of prenatal mercury exposure, is associated with risk for neural tube defects in offspring  [J]. Environment International, 2021, 150:106425. Doi: 10.1016/j.envint.2021.106425.

5. Jin L, Yu JR, Zhang L, Ren AG. Comparison of Plasma Concentrations of Mercury, Cadmium, and Arsenic among Women in 2005 and 2012 in a Historically Contaminated Area in China  [J]. Biol Trace Elem Res, 2020, 198(2): 380-9. Doi: 10.1007/s12011-020-02075-1.

6. Wang C, Jin L, Tong M, Zhang J, Yu J, Meng W, Jin L*. Prevalence of gestational diabetes mellitus and its determinants among pregnant women in Beijing  [J]. The Journal of Maternal-Fetal & Neonatal Medicine, 2020, 1-7. Doi: 10.1080/14767058.2020.1754395.

7. Jin L, Jin L, Yu J, Xu Y, Liu H, Ren A. Prevalence of Neural Tube Defects and the Impact of Prenatal Diagnosis in Three Districts of Beijing, China. Paediatric and perinatal epidemiology. 2017,31:293-300. Doi: 10.1111/ppe.12354.

8. Jin L, Liu, M, Zhang L, Li Z, Yu J, Liu J, Ye R, Chen L*, Ren A*. Exposure of methyl mercury in utero and the risk of neural tube defects in a Chinese population. Reproductive toxicology. 2016, 61:131-5. Doi: 10.1016/j.reprotox.2016.03.040.

9. Wang B, Jin L, Ren A*, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang L, Zhang Y, Wang X, Tao S, Finnell RH. Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring. Environ Sci Technol, 2015, 49(1): 588-96. Doi: 10.1021/es503990v. (并列第一作者)

10. Jin L, Liu J, Ye B, Ren A*. Concentrations of selected heavy metals in maternal blood and associated factors in rural areas in Shanxi Province, China. Environ Int, 2014, 66:157-164. Doi: 10.1016/j.envint.2014.01.016.