Dafang Chen

Professor
dafangchen@bjmu.edu.cn
Xueyuan Road 38, Haidian District, Beijing, China
Peking University

Personal profile

Department of Epidemiology and Health Statistics, Peking University，main research directions are Molecular Epidemiology of Chronic Diseases and Data Mining. The Director of the Health Care Management Committee, China Medicine Education Association；Associate Director of Patient Experience Management and Evaluation Committee, Chinese Research Hospital Association; Standing committee of Precision Cardiovascular Group, Cardiology Branch Committee of Chinese Medical Association; Standing committee of Cardiovascular Disease Prevention and Treatment Branch Committee, China Healthcare International Exchange Promotion Association. Ever used to be deputy director of the Center for Ecological Genetics of Peking University and deputy director of the Department of Medical Genetics at the School of Basic Medicine. As a senior visiting scholar, I studied population genetics and biostatistics at Harvard University in the United States from 1998 to 2000. I was awarded the second prize of Beijing Science and Technology Progress Award and one third prize. Published more than 200 research papers, including more than 90 SCI papers.

Main research directions

Molecular Epidemiology of Chronic Diseases, Data Mining

Representative scientific research projects

1.Molecular Genetic Epidemiology Study of Low Birth Weight(Key Project of National Family Planning Commission, 2000-2004, Co-PI).

2.Cancer patient's immune status assessment (Key Project of Beijing Science and Technology Commission, 2002-2006, Co-PI).

3.Early Diagnosis of Depression and Standardized Comprehensive Therapy Model（National 11th Five-Year Project, 2008—2012, Co-PI).

4.Study on the Carcinogenicity and Molecular Mechanism of Human Papilloma Virus (HPV) in High Esophageal Cancer Population（Key Project of National Natural Science Foundation of China, 2008-2012, Co-PI).

5.Genetic Epidemiology Study of Multiple Pathway Gene Polymorphisms Associated with Ischemic Stroke（National Natural Science Foundation of China, 2009-2012,Co-PI).

6.Screening and testing technical services for early diagnosis of major diseases（2011-2015, PI).

7.Establishment and Evaluation of Adult Type 2 Diabetes Risk Model in Fangshan District of Beijing（National Natural Science Foundation of China, 2012-2015, PI).

8.Establishment and evaluation of index system for acute myocardial infarction in China（Chinese Medical Doctor Association Cooperation Project, 2016-2018, PI).

9.Data Mining for Project of Acute Myocardial Infarction in China（Sanofi China Cooperation Project, 2017-2018, PI).

10.EPICOR Asia China Extended Follow-Up Study of Coronary heart disease(AstraZeneca China Cooperation Project, 2017-2019, PI).

11.Study on Gene Polypeptidy of Metabolic Syndrome Based on Inconsistent Siblings(Beijing Nature Fund, 2018-2021, PI).

10 representative papers

1.Jun Zhang, Feng Zhou, Xu Ran, Ping Ye, Si Chen, Xiaotong Dai, Dafang Chen, Baoguo Jiang. Reliability and validity an indicator system used to evaluate outpatient and inpatient satisfaction in Chinese hospitals.Patient Preference and Adherence. 2018:12. 2527–2536.

2.Qiwen Zheng, Hui Liu, Jun Zhang, Dafang Chen. The Effect of Ambient Particle Matters on Hospital Admissions for Cardiac Arrhythmia: A multi-city case-crossover study in China. Environmental Health, 2018 Jul 16;17(1):60. doi: 10.1186/s12940-018-0404-z.

3.Xiaotong Dai, Hui Liu, Dafang Chen, Jun Zhang. Association between ambient particulate matter concentrations and hospitalization for ischemic heart disease (I20-I25, ICD-10) in China: A multicity case-crossover study. Atmospheric Environment 186 (2018) 129–135.

4.Si Chen, Ying Yang, Guan-Liang Cheng, Jia Jia, Fang-Fang Fan,Jian-Ping Li,Yong Huo, Yan Zhang, Da-Fang Chen. Association between short sleep duration and carotid atherosclerosis in Chinese Community Population. J Epidemiol Community Health. 2018 Jun;72(6):539-544.

5.Keye Wu， Aiqun Huang， Si Chen， Wei Zhao， Huanqing Hu， Qi Yang; Dafang Chen. Arrendance at prenatal care and adverse birth outcomes in China: a follow-up study based on Maternal and Newborn’s Health Monitoring System. Midwifery, 57（2018）26-31.

6.Xiaozhu Wang, Yu Huang, Ming Yan, Jiuwei Li, Changhong Ding, Hong Jin, Fang Fang, Yanling Yang, Baiyan Wu, Dafang Chen. Molecular spectrum of excision repair cross-complementation group 8 gene defects in Chinese patients with Cockayne syndrome type A. Scientific Reports 7, Article number: 13686 (2017) doi:10.1038/s41598-017-14034-3.

7.Liu ZK, Wu KY, Dai XT, Che QZ, Chen S, Jia J2, Li JP, Huo Y, Zhang Y, Chen DF. The grading effect of abnormal glucose status on arterial stiffness and a new threshold of 2-hour post-load glucose based on a Chinese community study.J Diabetes Investig. 2017 Sep 1. doi: 10.1111/jdi.12741.

8.Duan F, Guo Y, Zhang L, Chen P, Wang X, Liu Z, Hu Y, Chen S, Chen D. Association of KCNQ1 polymorphisms with gliclazide efficacy in Chinese type 2 diabetic patients. Pharmacogenetics and Genomics. 26(4):178–183, APR 2016.

9.Liu-wei ZHANG, Jian-ping LI, Fang-fang DUAN, Zhi-ke Liu, Zi-qing Ma, Jin LI, Jie Jiang, Yan Zhang, Yong HUO, Da-fang CHEN. Synergistic effect of type 2 diabetes mellitus with Chromosome 9p21 rs10757274 polymorphism on the risk of myocardial infarction: a case-control study in Chinese population. BMC Cardiovascular Disorders. 2014,14:170.

10.Di-Qing Luo, Xiao-Zhu Wang, Yan Meng, Ding-Yang He, Ying-Ming Chen, Zhi-Yong Ke, Ming Yan,Yu Huang and Da-Fang Chen. Mandibuloacral dysplasia type A-associated progeria caused by homozygous LMNA mutation in a family from Southern China. BMC Pediatrics 2014, 14:256.